PCSK9 inhibitors: when statins aren't enough
نویسندگان
چکیده
منابع مشابه
Managing the Hypercholesterolemic Patient: When Statins Are Not Enough
OBJECTIVES After participating in the CME activity, primary care physicians should be able to: 1. Understand the fundamental concepts in cardiovascular risk stratification in hypercholesterolemic subjects based on new cholesterol guidelines 2. Recognize the common secondary causes of hypercholesterolemia and the choice of laboratory studies to identify patients with these disorders 3. Understan...
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Alirocumab and evolocumab are monoclonal antibodies that block proprotein convertase subtilisin/kexin type 9 (PCSK9), a circulating protein that degrades low-density lipoprotein (LDL) receptors. These therapies increase LDL receptors on the cell surface and reduce plasma LDL cholesterol. Both therapies are approved to lower LDL cholesterol, a causative agent for atherosclerotic cardiovascular d...
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ژورنال
عنوان ژورنال: Prescriber
سال: 2017
ISSN: 0959-6682
DOI: 10.1002/psb.1616